Combating colorectal lung metastases via systemic therapy and thermal ablation: RAS mutation impact
RAS mutations are independent predictors of poor local control and survival after IGTA in CRLM. Evaluate interactions between RAS genotype and commonly used targeted agents in the peri-ablative setting. These integrated, real-world insights support the development of genotype-guided ablation planning and peri-ablative systemic therapy strategies.
Authors
- Jiangping Cun
- Chunlong Fu (ORCID: https://orcid.org/0000-0003-4858-671X)
- Hua Fan (ORCID: https://orcid.org/0000-0001-7731-7207)
- Xinghai Li (ORCID: https://orcid.org/0009-0003-7532-0391)
- Xuancheng Xie
- An Li (ORCID: https://orcid.org/0000-0002-2834-3748)
- Xiangwen Xia
- Fenhua Zhao
- Jihong Hu
- Bufu Tang
- Shufeng Xu
- Tao Xu
- Rong Ding
- Yulan Zeng
- Jiahua Zou
Institutions
- Union Hospital (HK)
- Sun Yat-sen University (CN)
- Fudan University (CN)
- Kunming Medical University (CN)
- Wenzhou Medical University (CN)
- First People's Hospital of Yunnan Province (CN)
- Ganzhou People's Hospital (CN)
- Hubei Provincial Hospital of Traditional Chinese Medicine (CN)
- Hubei Provincial Center for Disease Control and Prevention (CN)
- Hubei University of Arts and Science (CN)
- Xiangyang Central Hospital (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
- Quzhou University (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Dongyang People's Hospital (CN)
- Huanggang Central Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1097/js9.0000000000004089
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00