Dynamic lysine acetylation and succinylation of platelet proteins regulates platelet storage lesion: mechanistic insights from multi-omics
By mapping the interplay between proteomic abundance shifts and PTM dynamics, this study provides a multidimensional understanding of PSL, establishing a foundational framework for optimizing storage protocols and enhancing transfusion safety.
Authors
- Xin Liao (ORCID: https://orcid.org/0000-0001-5026-2824)
- Min Chen (ORCID: https://orcid.org/0000-0003-2947-7921)
- Zi Wang (ORCID: https://orcid.org/0000-0002-3953-0493)
- Xiaolei Hu (ORCID: https://orcid.org/0009-0001-2198-6222)
- Li Wang
- Chenlu Zhang
- Xinpeng Luo
- Jianfeng Zhou
Institutions
- New York Blood Center (US)
- Guangzhou Blood Center (CN)
- Ministry of Education (TH)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Huashan Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1080/07853890.2026.2635200
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00