Variants in Genes Encoding Innate Lymphoid Cells Type 2 Surface Markers Affecting Asthma and Atopy Pathologies

Summary Genetic polymorphisms on ILC2 receptors (CD127, IL‐17RB and CRTH2) increase the asthma and atopy susceptibilities. Cohort analysis suggests that alleles' combination from ILC2 variants contributes to asthma and atopy risk.

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Publication Details

Journal
Clinical & Experimental Allergy
Published
2026-02-22
DOI
https://doi.org/10.1111/cea.70249
Primary Topic
IL-33, ST2, and ILC Pathways
Type
article
Field-Weighted Citation Impact
0.00

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article

Variants in Genes Encoding Innate Lymphoid Cells Type 2 Surface Markers Affecting Asthma and Atopy Pathologies

Talita dos Santos de Jesus, Raphael Chagas Silva, Cínthia Vila Nova Santana, R. V. Oliveira et al.
Clinical & Experimental Allergy
IL-33, ST2, and ILC Pathways
article

Variants in Genes Encoding Innate Lymphoid Cells Type 2 Surface Markers Affecting Asthma and Atopy Pathologies

Talita dos Santos de Jesus, Raphael Chagas Silva, Cínthia Vila Nova Santana, R. V. Oliveira, Gabriela Pimentel Pinheiro, Álvaro Augusto Cruz, Dos Santos Costa R, Kathleen C Barnes, Camila Alexandrina Figueiredo, Jamille Souza Fernandes Chiarelotto, Carolina Melo Orrico‐Ferreira, Hátilla dos Santos Silva, Neuza Maria A. Neves, Carina da Silva Pinheiro
article en

Abstract

Summary Genetic polymorphisms on ILC2 receptors (CD127, IL‐17RB and CRTH2) increase the asthma and atopy susceptibilities. Cohort analysis suggests that alleles' combination from ILC2 variants contributes to asthma and atopy risk.

Clinical & Experimental Allergy
Universidade Federal da Bahia (BR), Universidade Federal do Oeste da Bahia (BR), Fundação Oswaldo Cruz (BR), University of Colorado Denver (US)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico
Openalex Percentile: Top 45%
IL-33, ST2, and ILC Pathways
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