Integration of metabolomics and transcriptomics to reveal metabolic characteristics and the role of mTORC1 in β-cell proliferation induced by a short-term high-fat diet

Our study confirms the significant role of the mTORC1 signaling pathway in pancreatic β-cell proliferation induced by a short-term high-fat diet.

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Publication Details

Journal
PeerJ
Published
2026-02-23
DOI
https://doi.org/10.7717/peerj.20871
Primary Topic
Pancreatic function and diabetes
Type
article
Field-Weighted Citation Impact
0.00
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article

Integration of metabolomics and transcriptomics to reveal metabolic characteristics and the role of mTORC1 in β-cell proliferation induced by a short-term high-fat diet

Y. X. Li, Shan Huang, Jing Li, Mengran Liu et al.
PeerJ
Pancreatic function and diabetes
article

Integration of metabolomics and transcriptomics to reveal metabolic characteristics and the role of mTORC1 in β-cell proliferation induced by a short-term high-fat diet

Y. X. Li, Shan Huang, Jing Li, Mengran Liu, Wenyi Li, Jiajia Wang
article en

Abstract

Our study confirms the significant role of the mTORC1 signaling pathway in pancreatic β-cell proliferation induced by a short-term high-fat diet.

PeerJVol. 14
Shanghai Jiao Tong University (CN), Shanghai University of Traditional Chinese Medicine (CN), Tongren Hospital (CN), Seventh People's Hospital of Shanghai (CN)
Openalex Percentile: Top 46%
Pancreatic function and diabetes
DOIOpen Access PDFOpenAlex
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