Human herpesvirus 6 and non-human herpesvirus 6 limbic encephalitis in children with allogeneic stem cell transplantation: A case series
A DWI abnormality of the hippocampal CA1 area is a good biomarker for the diagnosis of HHV-6-positive or -negative PALE in children. Glutamatergic dysregulation and hippocampal cytotoxic edema may be involved in PALE.
Authors
- Jun Natsume (ORCID: https://orcid.org/0000-0002-2081-9449)
- Anna Shiraki (ORCID: https://orcid.org/0000-0002-4327-7777)
- Hajime Narita (ORCID: https://orcid.org/0009-0000-1414-7802)
- Fumi Sawamura (ORCID: https://orcid.org/0000-0003-3169-1169)
- JUN-ICHI KAWADA
- Ryosuke Suzui
- Daichi Sajiki (ORCID: https://orcid.org/0000-0003-4262-683X)
- Sumire Kumai
- Hiroyuki Kidokoro (ORCID: https://orcid.org/0000-0002-7991-8580)
- Yuji Ito (ORCID: https://orcid.org/0009-0007-3640-716X)
- Shiro Ozasa
- Tsu Yoshimura
- Tomohiko Nakata
- Takashi Shibata
- Hideki Muramatsu
- Hiroyuki Yamamoto
- Yoshiyuki Takahashi
Institutions
- Fujita Health University (JP)
- Okayama University (JP)
- Okayama University Hospital (JP)
- Kumamoto University Hospital (JP)
- Nagoya University (JP)
Publication Details
- Journal
- Brain and Development
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1016/j.braindev.2026.104514
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00