SENOPAUSE: Evaluation of an ASCO-Derived Clinical Proxy for Axillary Risk Stratification in a Retrospective Cohort

In a real-world cohort meeting strict ASCO proxy criteria, approximately 1 in ten patients had occult pN1 disease, yet chemotherapy use remained uncommon and WBRT was near-universal. These findings suggest nodal status may have limited impact on downstream adjuvant treatment escalation in highly selected low-risk luminal breast cancers.

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Publication Details

Journal
Clinical Breast Cancer
Published
2026-02-23
DOI
https://doi.org/10.1016/j.clbc.2026.02.013
Primary Topic
Dermatologic Treatments and Research
Type
article
Field-Weighted Citation Impact
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article

SENOPAUSE: Evaluation of an ASCO-Derived Clinical Proxy for Axillary Risk Stratification in a Retrospective Cohort

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SENOPAUSE: Evaluation of an ASCO-Derived Clinical Proxy for Axillary Risk Stratification in a Retrospective Cohort

Léa Pauly, Leslie Elahi, Eugénie Guillot, Nicolas Pouget, Louise Maumy, Michel Gabriel CAZENAVE, Katia MAHIOU, Mathis Trotin, Grégoire Miahlhe, Claire Bonneau, Louise Benoit
article en

Abstract

In a real-world cohort meeting strict ASCO proxy criteria, approximately 1 in ten patients had occult pN1 disease, yet chemotherapy use remained uncommon and WBRT was near-universal. These findings suggest nodal status may have limited impact on downstream adjuvant treatment escalation in highly selected low-risk luminal breast cancers.

Clinical Breast CancerVol. 26(4)
Université de Versailles Saint-Quentin-en-Yvelines (FR), Université Paris-Saclay (FR), Institut Curie (FR)
Zero hunger
Openalex Percentile: Top 45%
Dermatologic Treatments and Research
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