A randomized, double-blind, placebo-controlled trial of olanzapine versus placebo plus ondansetron and dexamethasone for antiemetic prophylaxis in patients receiving oxaliplatin-, irinotecan-, or carboplatin-based chemotherapy
Olanzapine (5 mg) combined with ondansetron and dexamethasone was associated with a moderate improvement in total protection and significant improvements in no-nausea and total control rates.
Authors
- Suthinee Ithimakin (ORCID: https://orcid.org/0000-0002-4205-6112)
- Apirom Laocharoenkeat
- Phurita Thongkijpreecha
- Akarin Nimmannit (ORCID: https://orcid.org/0000-0001-7937-2306)
- Chayanis Kositamongkol (ORCID: https://orcid.org/0000-0001-7182-0733)
- Pochamana Phisalprapa (ORCID: https://orcid.org/0000-0003-1995-4405)
- Warangkana Harikul
Institutions
- Siriraj Hospital (TH)
- Mahidol University (TH)
Publication Details
- Journal
- Supportive Care in Cancer
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1007/s00520-026-10490-8
- Primary Topic
- Nausea and vomiting management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Mahidol University
- Faculty of Medicine Siriraj Hospital, Mahidol University