Differences in the expression profiles of m6A-related genes and the prognostic role in immunotherapy for lung adenocarcinoma patients

Our findings suggest that the m6A modification influences the tumor microenvironment and that IGF2BP1 acts as an independent predictor of immunotherapy response in LUAD. It may serve as an innovative biomarker for LUAD prognosis and tumor immunity status.

Authors

Institutions

Publication Details

Journal
Frontiers in Oncology
Published
2026-02-23
DOI
https://doi.org/10.3389/fonc.2026.1751029
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Differences in the expression profiles of m6A-related genes and the prognostic role in immunotherapy for lung adenocarcinoma patients

Xikun Zhang, Yang Yang, Zhizhao Zhang, Chen Xue et al.
Frontiers in Oncology
RNA modifications and cancer
article

Differences in the expression profiles of m6A-related genes and the prognostic role in immunotherapy for lung adenocarcinoma patients

Xikun Zhang, Yang Yang, Zhizhao Zhang, Chen Xue, Guangyang Bai
article en

Abstract

Our findings suggest that the m6A modification influences the tumor microenvironment and that IGF2BP1 acts as an independent predictor of immunotherapy response in LUAD. It may serve as an innovative biomarker for LUAD prognosis and tumor immunity status.

Frontiers in OncologyVol. 16
Henan University of Science and Technology (CN), Shandong Provincial Hospital (CN), Qinghai Provincial Peoples Hospital (CN), Shandong First Medical University (CN)
Good health and well-being
Openalex Percentile: Top 45%
RNA modifications and cancer
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.