Epidemiology of drug–resistant tuberculosis in Hunan China over a 10–year period

This study presents a 10-year epidemiological assessment of DR-TB in Hunan Province, China, covering 2014-2023. A disproportionately high burden was observed among middle-aged and older male farmers. The predominance of INH-R TB and MDR-TB, together with distinct regional and demographic risk profiles, underscores an urgent need to strengthen TB control measures. These results support the implementation of targeted interventions, including intensified screening in high-risk populations and in high-incidence areas, along with optimized treatment regimens, to curb the ongoing DR-TB epidemic in South-Central China.

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Publication Details

Journal
Frontiers in Public Health
Published
2026-02-23
DOI
https://doi.org/10.3389/fpubh.2026.1771140
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00

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article

Epidemiology of drug–resistant tuberculosis in Hunan China over a 10–year period

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Frontiers in Public Health
Tuberculosis Research and Epidemiology
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Epidemiology of drug–resistant tuberculosis in Hunan China over a 10–year period

Fanyan Luo, Hua Bai, Jingwei Guo, Yunhong Tan, Jue Wang, Di Zhou, Wenbin Li, Xi Yang, Zhenhua Chen, Yi Liu, Jie Duan, Wang Peng, Xiaojie Wan, Xuan Zeng
article en

Abstract

This study presents a 10-year epidemiological assessment of DR-TB in Hunan Province, China, covering 2014-2023. A disproportionately high burden was observed among middle-aged and older male farmers. The predominance of INH-R TB and MDR-TB, together with distinct regional and demographic risk profiles, underscores an urgent need to strengthen TB control measures. These results support the implementation of targeted interventions, including intensified screening in high-risk populations and in high-incidence areas, along with optimized treatment regimens, to curb the ongoing DR-TB epidemic in South-Central China.

Frontiers in Public HealthVol. 14
Hunan Province Chest Hospital (CN), University of South China (CN), Guangzhou Medical University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Hunan Province, National Key Research and Development Program of China
Good health and well-being
Openalex Percentile: Top 46%
Tuberculosis Research and Epidemiology
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