Serelaxin Alleviates Ischemia Reperfusion-Induced Kidney Injury By Modulating Inflammatory Response And Inhibiting Of Notch-2/Hes-1 Signaling Pathway
These results highlight the nephroprotective effects of serelaxin against IRI by numerous pathways that also include Notch-2/Hes1. These novel findings uphold the use of serelaxin or serelaxin derived agents as a promising medication for those illnesses in which IRI is the main pathogen.
Authors
- Thu-Alfeqar R. Tweij
- Esraa A. Alyasiry
- Atheer Mohammed Jasim Al-Zurfi
- Shahad Ali Mohammed Rabeea
Institutions
- University of Alkafeel (IQ)
- University of Al Maarif (IQ)
- University of Kufa (IQ)
Publication Details
- Journal
- Pakistan Journal of Pharmaceutical Sciences
- Published
- 2026-02-11
- DOI
- https://doi.org/10.36721/pjps.2026.39.4.reg.13820.1
- Primary Topic
- Organ Transplantation Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00