Metabolism, Not Mendacity: Rethinking Prolonged Cocaine Positivity

Prolonged cocaine metabolite detection can reflect delayed metabolic clearance rather than continued use. Awareness of pharmacokinetic and pharmacogenomic factors is essential for accurate urine toxicology interpretation and patient-centered addiction care.

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Publication Details

Journal
Journal of Addiction Medicine
Published
2026-02-23
DOI
https://doi.org/10.1097/adm.0000000000001664
Primary Topic
Pharmacogenetics and Drug Metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Metabolism, Not Mendacity: Rethinking Prolonged Cocaine Positivity

Maryam Dehghani Soltani, Daniel M. Bowen
Journal of Addiction Medicine
Pharmacogenetics and Drug Metabolism
article

Metabolism, Not Mendacity: Rethinking Prolonged Cocaine Positivity

Maryam Dehghani Soltani, Daniel M. Bowen
article en

Abstract

Prolonged cocaine metabolite detection can reflect delayed metabolic clearance rather than continued use. Awareness of pharmacokinetic and pharmacogenomic factors is essential for accurate urine toxicology interpretation and patient-centered addiction care.

Journal of Addiction Medicine
Naval Medical Center San Diego (US), University of California San Diego (US), VA San Diego Healthcare System (US), National Patient Safety Foundation (US)
Good health and well-being
Openalex Percentile: Top 45%
Pharmacogenetics and Drug Metabolism
DOISourceOpenAlex
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