Combined assessment of ERO1A expression and CD163+ tumor-associated macrophage infiltration is superior to traditional assessment methods in predicting clear cell renal cell carcinoma prognosis

Compared with currently available biomarkers, the combination of ERO1A expression and the density of infiltrating CD163<sup>+</sup> TAMs with TNM stage or the SSIGN score exhibits greater accuracy in evaluating ccRCC patient survival.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-23
DOI
https://doi.org/10.3389/fonc.2026.1732415
Primary Topic
Immune cells in cancer
Type
article
Field-Weighted Citation Impact
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article

Combined assessment of ERO1A expression and CD163+ tumor-associated macrophage infiltration is superior to traditional assessment methods in predicting clear cell renal cell carcinoma prognosis

Mierxiati Abudurexiti, Changjie Ren, Huaye Wu, Hao Xiang et al.
Frontiers in Oncology
Immune cells in cancer
article

Combined assessment of ERO1A expression and CD163+ tumor-associated macrophage infiltration is superior to traditional assessment methods in predicting clear cell renal cell carcinoma prognosis

Mierxiati Abudurexiti, Changjie Ren, Huaye Wu, Hao Xiang, Tianyu Hong, Y. C. Yu, Zhong Wang, Chao Wang
article en

Abstract

Compared with currently available biomarkers, the combination of ERO1A expression and the density of infiltrating CD163<sup>+</sup> TAMs with TNM stage or the SSIGN score exhibits greater accuracy in evaluating ccRCC patient survival.

Frontiers in OncologyVol. 16
University of Shanghai for Science and Technology (CN), Second Military Medical University (CN), Chengdu Women's and Children's Central Hospital (CN), Changhai Hospital (CN), First People’s Hospital of Zunyi (CN), Shanghai Pudong New Area Gongli Hospital (CN)
Good health and well-being
Openalex Percentile: Top 45%
Immune cells in cancer
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