Cytomegalovirus-specific CD154-expressing T Cells are Present Before Transplantation in Cytomegalovirus-seronegative Recipients and Predict Early Cytomegalovirus DNAemia

CMV-specific T cells that express CD154 demonstrate protective levels of CMI in half of all seronegative recipients and can be used to optimize antiviral prophylaxis across all risk categories.

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Publication Details

Journal
Transplantation Direct
Published
2026-02-23
DOI
https://doi.org/10.1097/txd.0000000000001923
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
0.00
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article

Cytomegalovirus-specific CD154-expressing T Cells are Present Before Transplantation in Cytomegalovirus-seronegative Recipients and Predict Early Cytomegalovirus DNAemia

Mylarappa Ningappa, Ajay Khanna, Brandon W. Higgs, George Vincent Mazariegos et al.
Transplantation Direct
Cytomegalovirus and herpesvirus research
article

Cytomegalovirus-specific CD154-expressing T Cells are Present Before Transplantation in Cytomegalovirus-seronegative Recipients and Predict Early Cytomegalovirus DNAemia

Mylarappa Ningappa, Ajay Khanna, Brandon W. Higgs, George Vincent Mazariegos, M. G. Michaels, Dawn Wilkerson, Brianna Spishock, Tamara Fazzolare, Chethan Ashokkumar, Vikram Raghu, Lisa Remaley, Rakesh Sindhi, Paul Morgan, G. C. Bond, Armando Ganoza, Kyle Soltys, Michael Green
article en

Abstract

CMV-specific T cells that express CD154 demonstrate protective levels of CMI in half of all seronegative recipients and can be used to optimize antiviral prophylaxis across all risk categories.

Transplantation DirectVol. 12(3)
Children's Hospital of Pittsburgh (US), Plexision (United States) (US)
Good health and well-being
Openalex Percentile: Top 46%
Cytomegalovirus and herpesvirus research
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