Review of clinical advances in the procedural sedation application of remimazolam

As a novel benzodiazepine derivative, remimazolam overcomes the limitations of traditional sedatives, offering a new option for procedural sedation in palliative care. Its unique pharmacologic properties ensure rapid onset, controllable duration of action, and high safety, thereby enhancing clinical procedural efficiency and patient experience. This systematic review of its clinical applications provides scientific evidence for the rational and standardized use of remimazolam in clinical practice. Future research should focus on expanding its application in more complex clinical scenarios and conducting long-term safety and efficacy studies to further promote the widespread use of remimazolam in procedural sedation.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-02-23
DOI
https://doi.org/10.3389/fphar.2026.1740897
Primary Topic
Anesthesia and Sedative Agents
Type
article
Field-Weighted Citation Impact
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article

Review of clinical advances in the procedural sedation application of remimazolam

Shuancheng Bai, Qiwei Wang
Frontiers in Pharmacology
Anesthesia and Sedative Agents
article

Review of clinical advances in the procedural sedation application of remimazolam

Shuancheng Bai, Qiwei Wang
article en

Abstract

As a novel benzodiazepine derivative, remimazolam overcomes the limitations of traditional sedatives, offering a new option for procedural sedation in palliative care. Its unique pharmacologic properties ensure rapid onset, controllable duration of action, and high safety, thereby enhancing clinical procedural efficiency and patient experience. This systematic review of its clinical applications provides scientific evidence for the rational and standardized use of remimazolam in clinical practice. Future research should focus on expanding its application in more complex clinical scenarios and conducting long-term safety and efficacy studies to further promote the widespread use of remimazolam in procedural sedation.

Frontiers in PharmacologyVol. 17
Baotou Medical College (CN), Inner Mongolia Medical University (CN)
Openalex Percentile: Top 47%
Anesthesia and Sedative Agents
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