Clinical characteristics and outcomes in patients with early-onset locally advanced rectal cancer
Early-onset rectal cancer patients exhibit similar response rates and DFS compared to older patients, but appear to have worse OS. Further studies are needed to explore biological factors and post-recurrence treatment strategies that may influence these outcomes.
Authors
- Elisa Tiberi
- Andrea Pretta (ORCID: https://orcid.org/0000-0002-0262-9270)
- M. Scartozzi
- Gianluca Pretta
- Matteo Fraschini (ORCID: https://orcid.org/0000-0003-2784-6527)
- F. Pietrantonio
- Valeria Pusceddu (ORCID: https://orcid.org/0000-0003-4167-9091)
- Dario Spanu
- Pina Ziranu (ORCID: https://orcid.org/0000-0002-5659-7366)
- Luca Didaci (ORCID: https://orcid.org/0000-0003-4586-944X)
- Clelia Donisi
- G. Randon
- Erika Cimbro
- M. Puzzoni
- Veronica Dell’Utri
- Andrea Bottelli
- Stefano Mariani
- Rossana Berardi
- Riccardo Giampieri
- Gavino Faa
Institutions
- Marche Polytechnic University (IT)
- East Sussex County Council (GB)
- University of Cagliari (IT)
- Istituto Nazionale di Fisica Nucleare, Sezione di Cagliari (IT)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
Publication Details
- Journal
- Therapeutic Advances in Medical Oncology
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1177/17588359251379744
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00