Multicenter evaluation of the PASS score as a negative predictive tool and the impact of inter-observer variability in pheochromocytoma and paraganglioma risk stratification

In this multicenter cohort, the PASS system demonstrated high NPV and screening potential, but significant inter-observer variability remains a challenge. Simplification of the PASS system and enhanced pathologist training may improve reproducibility and clinical utility in PPGL risk stratification.

Authors

Institutions

Publication Details

Journal
Journal of Pathology and Translational Medicine
Published
2026-02-23
DOI
https://doi.org/10.4132/jptm.2025.11.05
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Multicenter evaluation of the PASS score as a negative predictive tool and the impact of inter-observer variability in pheochromocytoma and paraganglioma risk stratification

Jae-Kyung Won, Soon-Won Hong, Kyeong Cheon Jung, Chan Kwon Jung et al.
Journal of Pathology and Translational Medicine
Adrenal and Paraganglionic Tumors
article

Multicenter evaluation of the PASS score as a negative predictive tool and the impact of inter-observer variability in pheochromocytoma and paraganglioma risk stratification

Jae-Kyung Won, Soon-Won Hong, Kyeong Cheon Jung, Chan Kwon Jung, Young Lyun Oh, Hye-Ri Shin, Su-Jin Shin, Sungyeon Jung
article en

Abstract

In this multicenter cohort, the PASS system demonstrated high NPV and screening potential, but significant inter-observer variability remains a challenge. Simplification of the PASS system and enhanced pathologist training may improve reproducibility and clinical utility in PPGL risk stratification.

Journal of Pathology and Translational MedicineVol. 60(2)
Yonsei University (KR), Severance Hospital (KR), Samsung Medical Center (KR), Seoul National University Hospital (KR), Seoul National University Bundang Hospital (KR), Gangnam Severance Hospital (KR), The Catholic University of Korea Seoul St. Mary's Hospital (KR), Sungkyunkwan University (KR), Catholic University of Korea (KR)
Gender equality
Openalex Percentile: Top 47%
Adrenal and Paraganglionic Tumors
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.