Quantifying new threats to health and biomedical literature integrity from rapidly scaled publications and problematic research

These findings highlight potential risks to research integrity in areas such as public health and drug safety, and especially to the accessibility and interoperability principles central to Open Science and Findable, Accessible, Interoperable and Reusable data practices. We argue that permissive open-access data policies naturally facilitate exploitative workflows and that these findings add to the case for the safeguarding mechanisms to preserve the goals of Open Science.