Mo‐Rubbing abdominal improves metabolic homeostasis in type 2 diabetes mellitus mice via a jejunum‐specific <scp>GLP1</scp> ‐dependent mechanism
Mo-Rubbing abdominal effectively ameliorates T2DM symptoms and systemic metabolic dysregulation by activating the GLP1-GLP1R-IRS1/AMPK/mTOR pathway, particularly in the jejunum. These findings support Mo-Rubbing abdominal as a promising non-pharmacological intervention for T2DM, with potential benefits for preventing diabetes-associated complications.
Authors
- Hui Xu (ORCID: https://orcid.org/0000-0001-5517-3556)
- Qingbo Wei
- Jian Hu (ORCID: https://orcid.org/0000-0002-3072-809X)
- Lutao Li
- Xinyi He (ORCID: https://orcid.org/0000-0003-3086-9068)
- Yelin Wu
- Zhijie Zhang (ORCID: https://orcid.org/0000-0002-1276-787X)
- Lu Gan (ORCID: https://orcid.org/0000-0002-4862-3747)
- Camille Carrere Rivera
- Yue Chen
- Wei Liu
Institutions
- Macau University of Science and Technology (MO)
- Nanjing University of Chinese Medicine (CN)
- Nanjing Drum Tower Hospital (CN)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1111/dom.70563
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00