Traditional, central obesity, and metabolic indices: which metrics better reflect osteoarthritis risk? A cross-sectional study in U.S. adults
Central adiposity indices (WWI, C-index) demonstrated stronger associations with OA prevalence than traditional and metabolic metrics, potentially through their dual sensitivity to biomechanical stress and adipokine dysregulation. While combining BMI with WWI or C-index may improve research-based risk profiling, future studies should establish population-specific reference ranges before considering clinical application.
Authors
- Hongfei Xue (ORCID: https://orcid.org/0000-0001-9691-9668)
- Aifeng Liu (ORCID: https://orcid.org/0000-0002-1403-4565)
- Longyao Zhang (ORCID: https://orcid.org/0000-0001-5363-8575)
- Peijian Wang (ORCID: https://orcid.org/0000-0002-3622-4538)
- Kuiliang Gao
- Chao Zhang
- Wenda Li
- Yifan Zhang
- Jiankang Xu
- Peisen Dai
Institutions
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1097/js9.0000000000003805
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00