Maternal vaginal colonisation with Neisseria meningitidis serogroup B and late onset neonatal invasive meningococcal disease

Here we report a case of late onset neonatal invasive meningococcal disease that was vertically transmitted, with maternal vaginal swab at the time of delivery and neonatal cerebrospinal fluid culture positive for <i>Neisseria meningitidis</i>. Whole genome sequencing of meningococcal isolates in the neonatal cerebrospinal fluid and maternal vaginal found both Men-B ST-2506 (clonal complex 32) and identical (1 SNP difference on split kmer analysis).

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Publication Details

Journal
Communicable Diseases Intelligence
Published
2026-02-23
DOI
https://doi.org/10.33321/cdi.2026.50.017
Primary Topic
Bacterial Infections and Vaccines
Type
article
Field-Weighted Citation Impact
0.00
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article

Maternal vaginal colonisation with Neisseria meningitidis serogroup B and late onset neonatal invasive meningococcal disease

Nadiya Brell, Monica Lahra, Martin Weber, Chloe Story et al.
Communicable Diseases Intelligence
Bacterial Infections and Vaccines
article

Maternal vaginal colonisation with Neisseria meningitidis serogroup B and late onset neonatal invasive meningococcal disease

Nadiya Brell, Monica Lahra, Martin Weber, Chloe Story, Sebastiaan Van Hal
article en

Abstract

Here we report a case of late onset neonatal invasive meningococcal disease that was vertically transmitted, with maternal vaginal swab at the time of delivery and neonatal cerebrospinal fluid culture positive for <i>Neisseria meningitidis</i>. Whole genome sequencing of meningococcal isolates in the neonatal cerebrospinal fluid and maternal vaginal found both Men-B ST-2506 (clonal complex 32) and identical (1 SNP difference on split kmer analysis).

Communicable Diseases IntelligenceVol. 50
New South Wales Department of Health (AU), Royal Prince Alfred Hospital (AU), Wollongong Hospital (AU), UNSW Sydney (AU), Prince of Wales Hospital (AU)
Zero hunger
Openalex Percentile: Top 46%
Bacterial Infections and Vaccines
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