Prospective evaluation of medication-related problems and pharmacist interventions in liver transplant recipients

To our knowledge, this is the first and most comprehensive study applying the PCNE v.9.1 method to liver transplant recipients hospitalized in both ward and intensive care unit settings. The most prevalent MRPs were related to "treatment effectiveness," primarily caused by "dose selection" and "drug selection." Clinical pharmacists and physicians should particularly focus on these aspects when reviewing transplant patients' medication regimens. The results achieved in this study suggest that clinicians should exercise caution when prescribing new medications to transplant recipients with at least one comorbidity and a history of acute kidney injury.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-02-23
DOI
https://doi.org/10.3389/fphar.2026.1738563
Primary Topic
Pharmaceutical Practices and Patient Outcomes
Type
article
Field-Weighted Citation Impact
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article

Prospective evaluation of medication-related problems and pharmacist interventions in liver transplant recipients

Mefküre Durmuş, Zeynep Ülkü GÜN, Sezai Yılmaz, Sena Güzel Karahan et al.
Frontiers in Pharmacology
Pharmaceutical Practices and Patient Outcomes
article

Prospective evaluation of medication-related problems and pharmacist interventions in liver transplant recipients

Mefküre Durmuş, Zeynep Ülkü GÜN, Sezai Yılmaz, Sena Güzel Karahan, Ahmet Çakır
article en

Abstract

To our knowledge, this is the first and most comprehensive study applying the PCNE v.9.1 method to liver transplant recipients hospitalized in both ward and intensive care unit settings. The most prevalent MRPs were related to "treatment effectiveness," primarily caused by "dose selection" and "drug selection." Clinical pharmacists and physicians should particularly focus on these aspects when reviewing transplant patients' medication regimens. The results achieved in this study suggest that clinicians should exercise caution when prescribing new medications to transplant recipients with at least one comorbidity and a history of acute kidney injury.

Frontiers in PharmacologyVol. 17
Trakya University (TR), Karadeniz Technical University (TR), Inonu University (TR), University of Pharmacy Yangon (MM)
Good health and well-being
Openalex Percentile: Top 45%
Pharmaceutical Practices and Patient Outcomes
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