Efficacy of intravenous parecoxib in preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: a randomized controlled trial
Intravenous parecoxib was effective in reducing post-ERCP abdominal pain and showed a trend toward a lower incidence of post-ERCP pancreatitis (PEP) in both unselected and high-risk patients, without any serious adverse events. Therefore, intravenous parecoxib may represent a viable alternative for PEP prevention in settings where rectal nonsteroidal anti-inflammatory drugs are unavailable.
Authors
- Surawitch Sawathanon
- Siriboon Attasaranya (ORCID: https://orcid.org/0000-0001-7594-1428)
- Tanawat Jongraksak (ORCID: https://orcid.org/0000-0003-2190-5549)
- Thanawin Wong (ORCID: https://orcid.org/0000-0003-2868-841X)
- Jaksin Sottisuporn (ORCID: https://orcid.org/0000-0002-6254-2759)
- Pimsiri Sripongpun (ORCID: https://orcid.org/0000-0003-0007-8214)
- Nisa Netinatsunton (ORCID: https://orcid.org/0000-0002-3351-6252)
- Tummarong Charoenrit
- Tanawat Pattarapuntakul (ORCID: https://orcid.org/0000-0002-6582-9608)
- Thanapon Yaowmaneerat (ORCID: https://orcid.org/0000-0003-0867-4424)
- Suraphon Assawasuwannakit (ORCID: https://orcid.org/0000-0003-0367-6746)
- Siwanon Nawalerspanya (ORCID: https://orcid.org/0009-0009-9915-2234)
- Thanaput Kunlayawutipong
Institutions
- Nha Trang University (VN)
- Prince of Songkla University (TH)
- Kanchanaburi Rajabhat University (TH)
- Mahidol University (TH)
- Ramathibodi Hospital (TH)
- Chiang Mai University (TH)
- Srinakharinwirot University (TH)
- Walailak University (TH)
Publication Details
- Journal
- Surgical Endoscopy
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1007/s00464-026-12629-4
- Primary Topic
- Gallbladder and Bile Duct Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Prince of Songkla University
- Faculty of Medicine, Prince of Songkla University