cGAS/STING-mediated upregulation of NKG2D ligands in LSCs contributes to enhanced sensitivity to NK cells
These data indicated that the DNA damage response-mediated cGAS/STING/TBK1/IRF3 signalling pathway played an essential role in modulating NKG2D ligands expression in LSCs.
Authors
- H B Zhu (ORCID: https://orcid.org/0009-0001-4700-7299)
- Yan Ouyang
- Pengcheng Zhu (ORCID: https://orcid.org/0000-0002-1284-3342)
- Yilin Qin
- Qianmin Zhang
Institutions
- Childhood Leukemia Foundation (US)
- Gannan Medical University (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-02-23
- DOI
- https://doi.org/10.3389/fonc.2026.1764427
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00