Association Between Occupational Physical Work Exposure and Wild-Type Transthyretin Cardiomyopathy
ATTRwt-CM was associated with greater occupational upper-body mechanical stress. While a causal relationship cannot be established due to study design, the results are hypothesis generating for the development of ATTRwt-CM. Additionally, ATTRwt-CM patients had a greater burden of orthopedic and cardiovascular comorbidities including increased cardiovascular mortality.
Authors
- Bertil Ladefoged (ORCID: https://orcid.org/0000-0002-3749-6789)
- Michael Maeng
- Kevin KW. Olesen
- Steen H. Poulsen
Institutions
- Aarhus University Hospital (DK)
Publication Details
- Journal
- JACC Advances
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1016/j.jacadv.2026.102619
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00