Renal Solitary Fibrous Tumor With Local Recurrence Following Complete Surgical Resection: A Case Report

Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm that most commonly arises in the pleura. Renal SFT is extremely uncommon, and local recurrence after complete surgical resection is rarely reported. In our case, an 81-year-old woman underwent laparoscopic radical nephrectomy for an incidentally detected left renal mass. Histopathological and immunohistochemical analysis confirmed a malignant SFT, with STAT6 and CD34 positivity, and classified it as intermediate risk according to the modified Demicco model. Despite negative imaging at six months, local recurrence was detected one year postoperatively and confirmed by biopsy. Renal SFTs may demonstrate unpredictable biological behavior, including local recurrence after apparently complete resection. Close and long-term follow-up is essential for optimal patient management.

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Publication Details

Journal
Cureus
Published
2026-02-23
DOI
https://doi.org/10.7759/cureus.104123
Primary Topic
Soft tissue tumor case studies
Type
article
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0.00
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article

Renal Solitary Fibrous Tumor With Local Recurrence Following Complete Surgical Resection: A Case Report

Napoleon Moulavasilis, Eirini Thymara, Konstantinos Douroumis, Konstantinos Belogiannis et al.
Cureus
Soft tissue tumor case studies
article

Renal Solitary Fibrous Tumor With Local Recurrence Following Complete Surgical Resection: A Case Report

Napoleon Moulavasilis, Eirini Thymara, Konstantinos Douroumis, Konstantinos Belogiannis, Evangelos Fragkiadis, Thomas Kalfas, Konstandinos Stravodimos, Maria Papanikolaou, Penelope Korkolopoulou, Panagiotis A Panagopoulos
article en

Abstract

Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm that most commonly arises in the pleura. Renal SFT is extremely uncommon, and local recurrence after complete surgical resection is rarely reported. In our case, an 81-year-old woman underwent laparoscopic radical nephrectomy for an incidentally detected left renal mass. Histopathological and immunohistochemical analysis confirmed a malignant SFT, with STAT6 and CD34 positivity, and classified it as intermediate risk according to the modified Demicco model. Despite negative imaging at six months, local recurrence was detected one year postoperatively and confirmed by biopsy. Renal SFTs may demonstrate unpredictable biological behavior, including local recurrence after apparently complete resection. Close and long-term follow-up is essential for optimal patient management.

CureusVol. 18(2)
National and Kapodistrian University of Athens (GR)
Good health and well-being
Openalex Percentile: Top 48%
Soft tissue tumor case studies
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