Proteomic landscape of colorectal cancer liver metastasis: molecular signatures and novel therapeutic targets
Our work reveals that colorectal cancer liver metastasis involves targeted molecular changes rather than widespread cellular chaos. The biomarkers we identified could improve early detection of metastatic risk and guide more personalized treatment decisions for patients.
Authors
- Jinjun Shi (ORCID: https://orcid.org/0000-0001-9200-5068)
- Guoqing Wang (ORCID: https://orcid.org/0000-0001-9326-3755)
- Xiangyu Su
- Zhigang Zhang
- Hongyuan Shen
- Jia Li
Institutions
- Zhongda Hospital Southeast University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2026-02-23
- DOI
- https://doi.org/10.7717/peerj.20856
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00