Age-associated chemokine receptor expression profiles in human peripheral blood monocyte subsets predict cardiovascular disease risk
Aging is associated with distinct changes in monocyte chemokine receptor expression that relate to CAD severity. These findings identify age- and disease-associated monocyte immune features that may contribute to CAD progression.
Authors
- Jessica L. Allen (ORCID: https://orcid.org/0000-0003-2273-1800)
- Chantel McSkimming
- Angela Marie Taylor
- Sanjiv Kumar (ORCID: https://orcid.org/0000-0003-0844-5090)
- Yury I. Miller (ORCID: https://orcid.org/0000-0003-0521-7690)
- Ravi K. Komaravolu (ORCID: https://orcid.org/0000-0002-3167-8960)
- Fabrizio Drago (ORCID: https://orcid.org/0000-0002-8591-7103)
- Gabriel Valentín-Guillama
- Runpei Wu
- Klaus Ley (ORCID: https://orcid.org/0000-0003-1124-9592)
- Nandini Chatterjee
- Catherine C. Hedrick
- Christopher Durant
- Ahmad Alimadadi
- Coleen A. McNamara
Institutions
- Carter Center (US)
- La Jolla Institute for Immunology (US)
- University of San Diego (US)
- University of California San Diego (US)
- Augusta University Health (US)
- University of Virginia (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-23
- DOI
- https://doi.org/10.3389/fimmu.2026.1749366
- Primary Topic
- Chemokine receptors and signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health