Type 2 diabetes mellitus associated microRNAs in tuberculosis susceptibility: a systematic review and bioinformatic analysis
Shared miRNAs act as molecular nodes linking immunity and metabolism, providing a framework for biomarker development in TB-T2DM comorbidity. Their regulatory convergence suggests potential applications in diagnosis, prognosis, and therapeutic innovation, particularly in vulnerable populations where both diseases intersect. These findings underscore the importance of integrating immunometabolic biomarkers into personalized medicine strategies to address the dual burden of TB and T2DM.
Authors
- Mauricio Castañón-Arreola (ORCID: https://orcid.org/0000-0003-1286-8862)
- Mercedes Viettri (ORCID: https://orcid.org/0000-0002-3290-2952)
- Martha G. Torres (ORCID: https://orcid.org/0000-0002-1254-5345)
- Rodolfo Chavez-Dominguez (ORCID: https://orcid.org/0000-0002-4097-6011)
- Itzel Corona-Galvan
- Emilio Hernández-Diego
- Claudia Carranza
Institutions
- Universidad Autónoma de la Ciudad de México (MX)
- Instituto Nacional de Enfermedades Respiratorias (MX)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-02-23
- DOI
- https://doi.org/10.3389/fendo.2026.1760933
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Institute of Nuclear Energy Research