The role of <scp>CXCL10</scp> in high‐fat diet–induced skeletal muscle inflammation and atrophy

CXCL10 mediates HFD-induced skeletal muscle atrophy by promoting inflammation and proteolysis. CXCL10 neutralization mitigates such muscle loss and may represent a novel therapeutic strategy to preserve skeletal muscle mass under metabolic stress.

Authors

Tomoya Inoue
An Liyuan
Yu Hirata
Kenji Sugawara
Wataru Ogawa

Institutions

Kobe University (JP)

Publication Details

Journal: Journal of Diabetes Investigation
Published: 2026-02-22
DOI: https://doi.org/10.1111/jdi.70270
Primary Topic: Muscle Physiology and Disorders
Type: article
Field-Weighted Citation Impact: 0.00

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article

The role of CXCL10 in high‐fat diet–induced skeletal muscle inflammation and atrophy

Tomoya Inoue, An Liyuan, Yu Hirata, Kenji Sugawara et al.

Feb 22, 2026

Journal of Diabetes Investigation

Muscle Physiology and Disorders

article

The role of CXCL10 in high‐fat diet–induced skeletal muscle inflammation and atrophy

Tomoya Inoue, An Liyuan, Yu Hirata, Kenji Sugawara, Wataru Ogawa

February 22, 2026article en

Abstract

Journal of Diabetes Investigation

Kobe University (JP)

Zero hunger

Openalex Percentile: Top 45%

Muscle Physiology and Disorders

DOI Open Access PDF OpenAlex

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