Neutrophil-mediated delivery of curcumin-loaded manganese-doped zeolitic imidazolate framework-8 nanozymes for pulmonary arterial hypertension
NEMZC represents a safe, targeted, and multifunctional cell‑based nanoplatform that effectively alleviates PAH through dual antioxidant/anti‑inflammatory action and EndoMT inhibition, demonstrating strong potential for clinical translation.
Authors
- Jianjun Ge
- Tian-Shu Chu
- Chun Dai
- Xiang Li
- You-Pin Wan
Institutions
- University of Science and Technology of China (CN)
- Anhui Provincial Hospital (CN)
- West Anhui University (CN)
- Lu'an First People's Hospital (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1186/s12951-026-04148-0
- Primary Topic
- Advanced Nanomaterials in Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00