SLC31A1 knockdown mitigates post-MI heart failure via regulation of copper metabolism
SLC31A1 plays a disease-promoting role in HF after AMI by activating NLRP3/HMGB1-dependent macrophage cuproptosis, which is expected to be a potential biomarker for HF.
Authors
- Ling Qin (ORCID: https://orcid.org/0000-0001-7522-7494)
- Jie Sun
- Huanyu Zhou
- Qi Wei
Institutions
- Jilin University (CN)
- Jilin Province Tumor Hospital (CN)
- First Hospital of Jilin University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-23
- DOI
- https://doi.org/10.3389/fimmu.2026.1707203
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00