The effect of short-term consumption of Bifidobacterium bifidum on the gut microbiome of obese individuals

It is known that gut microbiota dysbiosis can lead to obesity by disrupting energy consumption and metabolism. Probiotic supplements are a potential therapeutic option for improving intestinal homeostasis. The aim of this study was to investigate the effect of a probiotic supplement containing <i>Bifidobacterium bifidum</i> on the intestinal microbiome of people with obesity using high-throughput sequencing on the DNBSEQ-G50 platform. The study demonstrated a positive effect of the supplement on bacterial species such as <i>Bacteroides uniformis</i>, <i>Alistipes putredinis</i>, <i>Alistipes shahii</i>, <i>Dysosmobacter welbionis</i>, and <i>Gemmiger formicilis</i>. Therefore, we suggest the potential use of this bacterial species in the treatment of gut microbiota dysbiosis of obese individuals.

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Publication Details

Journal
Experimental Biology and Medicine
Published
2026-02-23
DOI
https://doi.org/10.3389/ebm.2026.10894
Primary Topic
Gut microbiota and health
Type
article
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article

The effect of short-term consumption of Bifidobacterium bifidum on the gut microbiome of obese individuals

О. С. Корнеева, Inna Burakova, Mikhail Syromyatnikov, O. N. Kryukova et al.
Experimental Biology and Medicine
Gut microbiota and health
article

The effect of short-term consumption of Bifidobacterium bifidum on the gut microbiome of obese individuals

О. С. Корнеева, Inna Burakova, Mikhail Syromyatnikov, O. N. Kryukova, Polina Morozova, Yuliya Smirnova, Svetlana Pogorelova, Tatiana Kislova
article en

Abstract

It is known that gut microbiota dysbiosis can lead to obesity by disrupting energy consumption and metabolism. Probiotic supplements are a potential therapeutic option for improving intestinal homeostasis. The aim of this study was to investigate the effect of a probiotic supplement containing <i>Bifidobacterium bifidum</i> on the intestinal microbiome of people with obesity using high-throughput sequencing on the DNBSEQ-G50 platform. The study demonstrated a positive effect of the supplement on bacterial species such as <i>Bacteroides uniformis</i>, <i>Alistipes putredinis</i>, <i>Alistipes shahii</i>, <i>Dysosmobacter welbionis</i>, and <i>Gemmiger formicilis</i>. Therefore, we suggest the potential use of this bacterial species in the treatment of gut microbiota dysbiosis of obese individuals.

Experimental Biology and MedicineVol. 251
Voronezh State University of Engineering Technologies (RU), Voronezh State Institute of Physical Culture (RU), Voronezh State University (RU)
Affordable and clean energy
Openalex Percentile: Top 45%
Gut microbiota and health
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