The role of a multidisciplinary approach in non-melanoma skin cancer management

A multidisciplinary team (MDT) is fundamental for properly managing non-melanoma skin cancer (NMSC). Surgery is the first treatment choice for early-stage disease; however, in cases with a high risk of recurrence or when demolitive approaches would not achieve safe margins, radiotherapy (RT) or an MDT approach is required. We retrospectively revised the population evaluated at our weekly MDT meeting, and all patients were discussed. A case series of 130 patients visited from July 2021 to March 2024 was collected. In-person visits were performed. The male/female ratio was 69.5/31.5%. Elderly patients prevailed: the mean age was 79 years (range 29-102 years). Patients affected by Gorlin syndrome were 7, and solid transplant recipients were 4. Among patients, 66 were diagnosed with cutaneous squamous cell carcinoma (SCC) (58%), 52 had basal cell carcinoma (BCC) (40%), and 12 had both SCC and BCC (9.2%). Among patients with SCC, 24 received primary surgery (36.4%), 11 received RT (16.6%), and 25 were candidates for treatment with cemiplimab (37.9%). Six patients (9.1%) were indicated to undertake a dermatological follow-up associated with best supportive care for comorbidities and performance status.