Transcriptomic analysis reveals synaptic dysregulation and mitochondrial dysfunction in autism spectrum disorder

This analysis uncovers a distinct molecular signature in ASD, emphasizing the convergence of synaptic abnormalities and metabolic disruption. The findings provide valuable insights into the pathophysiology of ASD and highlight potential targets for biomarker development and therapeutic strategies.

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Publication Details

Journal
Brain Behavior & Immunity - Health
Published
2026-02-23
DOI
https://doi.org/10.1016/j.bbih.2026.101197
Primary Topic
Autism Spectrum Disorder Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Transcriptomic analysis reveals synaptic dysregulation and mitochondrial dysfunction in autism spectrum disorder

Jingqi Shao, Zhihui Chen, Xiaoli Liao
Brain Behavior & Immunity - Health
Autism Spectrum Disorder Research
article

Transcriptomic analysis reveals synaptic dysregulation and mitochondrial dysfunction in autism spectrum disorder

Jingqi Shao, Zhihui Chen, Xiaoli Liao
article en

Abstract

This analysis uncovers a distinct molecular signature in ASD, emphasizing the convergence of synaptic abnormalities and metabolic disruption. The findings provide valuable insights into the pathophysiology of ASD and highlight potential targets for biomarker development and therapeutic strategies.

Brain Behavior & Immunity - HealthVol. 53
Sun Yat-sen University (CN), Second People Hospital of Hunan (CN), Hunan Provincial People's Hospital (CN)
Openalex Percentile: Top 49%
Autism Spectrum Disorder Research
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