The cholesterol, high-density lipoprotein, and glucose (CHG) index as a novel metabolic marker for predicting adverse outcomes in myocardial infarction survivors: insights from two large prospective cohorts
In two large independent cohorts of individuals with prior MI, the CHG index was independently associated with risks of adverse events. While its independent discriminative power is modest, the index serves as a valuable adjunctive tool that enhances risk reclassification, warranting further validation in prospective clinical settings to confirm its utility in secondary prevention.
Authors
- Zhen’ge Chang (ORCID: https://orcid.org/0000-0002-2099-0887)
- Yanjun Song (ORCID: https://orcid.org/0000-0001-6678-7721)
- Kefei Dou
- Chunyue Wang
- Zhihao Zheng
- Xinyue Chen
- Jining He
- Rui Fu
- Zhangyu Lin
- Bowen Li
- Xiaohui Bian
- Chen Zhu
Institutions
- Chinese Center For Disease Control and Prevention (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Fu Wai Hospital (CN)
- State Key Laboratory of Cardiovascular Disease
- China Agricultural University (CN)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1186/s12933-026-03104-4
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science and Technology Major Project