Epigenetic Activity of Cancer Therapy Drugs Revealed by HeLa TI Cell-Based Assay
Our findings show that many anticancer therapy agents modulate the epigenetic landscape of cancer cells, providing a rationale for expanding their therapeutic applications and enhancing the efficacy of combination strategies by overcoming epigenetically driven chemoresistance.
Authors
- Aleksandr Kudriashov
- V. G. Popova (ORCID: https://orcid.org/0000-0002-7301-605X)
- Varvara Maksimova (ORCID: https://orcid.org/0000-0003-0896-2952)
- Gennady A. Belitsky (ORCID: https://orcid.org/0000-0002-3167-7204)
- Marianna G. Yakubovskaya (ORCID: https://orcid.org/0000-0002-9710-8178)
- Olga Usalka (ORCID: https://orcid.org/0000-0001-9525-0771)
- Alyona V. Kholodova
- Julia Makus
- Kirill I. Kirsanov
- Eugenia Lylova
Institutions
- Tufts University (US)
- Peoples' Friendship University of Russia (RU)
- Pirogov Russian National Research Medical University (RU)
- Ministry of Health (ES)
- Federal Agency for Health and Social Development (RU)
- Federal Medical-Biological Agency (RU)
Publication Details
- Journal
- Epigenomes
- Published
- 2026-02-23
- DOI
- https://doi.org/10.3390/epigenomes10010014
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Russian Science Foundation