Epidemiology of adult T-cell leukemia/lymphoma (ATL) in people living with HTLV-1: A 30-year study in Peru
This is the first study to describe ATL epidemiology in Peru from an infectious disease perspective. Most patients were unaware of their HTLV-1 status before developing ATL, highlighting missed opportunities for earlier detection. Routine HTLV-1 testing should be considered in the evaluation of T-cell malignancies in endemic countries. In addition, screening high-risk populations could support earlier diagnosis and reduce transmission. Improving access to diagnostic tools, along with stronger collaboration between infectious diseases and oncology services could improve patient outcomes in endemic regions.
Authors
- Carlos Seas (ORCID: https://orcid.org/0000-0002-8375-3440)
- Martín Montes (ORCID: https://orcid.org/0000-0002-7427-347X)
- Elsa González-Lagos (ORCID: https://orcid.org/0000-0002-8543-8188)
- Gabriela Garrido-Pinzas (ORCID: https://orcid.org/0000-0002-6930-8893)
- Luis Malpica
- Fernando Mejía
- Brian Valenzuela
- Juan Carlos Ramos
- Carolina Álvarez
- Eduardo Gotuzzo
- Victor Rivera
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- Universidad Peruana Cayetano Heredia (PE)
- Hospital Nacional Cayetano Heredia (PE)
- Sylvester Comprehensive Cancer Center (US)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1371/journal.pntd.0014010
- Primary Topic
- T-cell and Retrovirus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00