Fluorescence Properties of Collagen Types I-V: A Comprehensive Study of Spectral and Lifetime Characteristics

This study establishes a comprehensive reference dataset for the fluorescence properties of collagen Types I-V and demonstrates the potential of combined I-EEMs and TR-EEMs analysis for tissue characterization. The results highlight species-, organ-, type-, and environment-specific optical fingerprints of similar collagens, which must be considered before implementing more in-depth studies on how the optical properties of collagen change in different medical applications.

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Publication Details

Journal
bioRxiv (Cold Spring Harbor Laboratory)
Published
2026-02-23
DOI
https://doi.org/10.64898/2026.02.21.706506
Primary Topic
Collagen: Extraction and Characterization
Type
article
Field-Weighted Citation Impact
0.00
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article

Fluorescence Properties of Collagen Types I-V: A Comprehensive Study of Spectral and Lifetime Characteristics

Laura Marcu, Xiangnan Zhou, Alexandra Adams, Xuhui Liu et al.
bioRxiv (Cold Spring Harbor Laboratory)
Collagen: Extraction and Characterization
article

Fluorescence Properties of Collagen Types I-V: A Comprehensive Study of Spectral and Lifetime Characteristics

Laura Marcu, Xiangnan Zhou, Alexandra Adams, Xuhui Liu, Julien Bec
article en

Abstract

This study establishes a comprehensive reference dataset for the fluorescence properties of collagen Types I-V and demonstrates the potential of combined I-EEMs and TR-EEMs analysis for tissue characterization. The results highlight species-, organ-, type-, and environment-specific optical fingerprints of similar collagens, which must be considered before implementing more in-depth studies on how the optical properties of collagen change in different medical applications.

bioRxiv (Cold Spring Harbor Laboratory)
Neurological Surgery (US), University of California, Davis (US)
Openalex Percentile: Top 47%
Collagen: Extraction and Characterization
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