Unmasking genetic etiologies in neurodevelopmental disorders characterized by Cerebral Palsy: insights from integrative genomic approaches
Our findings support the increasing evidence that genetic factors contribute significantly to CP etiology and emphasize the importance of integrating genomic testing into clinical evaluation. The systematic use of exome and genome sequencing improves diagnostic yield and enables genotype-informed classification, aiding targeted management and genetic counseling for affected individuals.
Authors
- Hülya Maraş Genç (ORCID: https://orcid.org/0000-0001-8869-0277)
- Hatice Gulhan Sözen
- Günseli Bayram Akçapınar (ORCID: https://orcid.org/0000-0002-6296-7415)
- Büşra Kutlubay (ORCID: https://orcid.org/0000-0002-6216-1438)
- P. Kara
- Özkan Özdemir (ORCID: https://orcid.org/0000-0002-2647-6416)
- Nihat Buğra Ağaoğlu (ORCID: https://orcid.org/0000-0002-9336-0552)
- Semih Ayta (ORCID: https://orcid.org/0000-0003-3355-9436)
- Ayca Yigit (ORCID: https://orcid.org/0009-0002-4174-923X)
- Ozlem Akgun-Dogan
- Ugur Ozbek
- Kaya Bilguvar
- Pınar Gencpinar
- Zeynep Ozkeserli
Institutions
- Bahçeşehir University (TR)
- Dokuz Eylül University (TR)
- Izmir Kâtip Çelebi University (TR)
- Ümraniye Eğitim ve Araştırma Hastanesi (TR)
- Institute for Biomedicine (IT)
- Children’s Foundation (GB)
- Krankenhaus Nordwest (DE)
- Kent Hastanesi (TR)
- Cancer Genetics (United States) (US)
- Pediatrics and Genetics (US)
- Kocaeli Üniversitesi (TR)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2026-02-23
- DOI
- https://doi.org/10.3389/fneur.2026.1742186
- Primary Topic
- Genomics and Rare Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu