Adsorption of colchicine, hydroxychloroquine, ibuprofen, and strychnine to activated charcoal

This study supports the targeted use of activated charcoal in colchicine, hydroxychloroquine, ibuprofen, and strychnine ingestions. Isotherm modeling reveals xenobiotic-specific differences in adsorption efficiency that may inform clinical decisions regarding dose, timing, and the potential use of additional charcoal administration.

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Publication Details

Journal
Clinical Toxicology
Published
2026-02-23
DOI
https://doi.org/10.1080/15563650.2026.2615838
Primary Topic
Poisoning and overdose treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Adsorption of colchicine, hydroxychloroquine, ibuprofen, and strychnine to activated charcoal

Stefanie A. Sydlik, Hunter B. Wood, Stella M. Trickett, Joseph T. Dosch et al.
Clinical Toxicology
Poisoning and overdose treatments
article

Adsorption of colchicine, hydroxychloroquine, ibuprofen, and strychnine to activated charcoal

Stefanie A. Sydlik, Hunter B. Wood, Stella M. Trickett, Joseph T. Dosch, Dazhe Cao
article en

Abstract

This study supports the targeted use of activated charcoal in colchicine, hydroxychloroquine, ibuprofen, and strychnine ingestions. Isotherm modeling reveals xenobiotic-specific differences in adsorption efficiency that may inform clinical decisions regarding dose, timing, and the potential use of additional charcoal administration.

Clinical Toxicology
Southwestern Medical Center (US), Carnegie Mellon University (US), The University of Texas Southwestern Medical Center (US)
Openalex Percentile: Top 50%
Poisoning and overdose treatments
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