Antihypertensive drug-induced adverse events in patients aged 80 years and older: A retrospective analysis using the Japanese Adverse Drug Event Report Database

This study, which employed the JADER database, identified specific AEs associated with drug use in patients aged ≥ 80 years. These AEs included syncope/loss of consciousness associated with β-blockers or CCBs as well as falls and edema associated with CCBs.

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Publication Details

Journal
International Journal of Clinical Pharmacology and Therapeutics
Published
2026-02-22
DOI
https://doi.org/10.5414/cp204943
Primary Topic
Pharmacovigilance and Adverse Drug Reactions
Type
article
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0.00
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article

Antihypertensive drug-induced adverse events in patients aged 80 years and older: A retrospective analysis using the Japanese Adverse Drug Event Report Database

Riku Matsushima, Masayuki Hashiguchi, Tsuyoshi Shiga
International Journal of Clinical Pharmacology and Therapeutics
Pharmacovigilance and Adverse Drug Reactions
article

Antihypertensive drug-induced adverse events in patients aged 80 years and older: A retrospective analysis using the Japanese Adverse Drug Event Report Database

Riku Matsushima, Masayuki Hashiguchi, Tsuyoshi Shiga
article en

Abstract

This study, which employed the JADER database, identified specific AEs associated with drug use in patients aged ≥ 80 years. These AEs included syncope/loss of consciousness associated with β-blockers or CCBs as well as falls and edema associated with CCBs.

International Journal of Clinical Pharmacology and Therapeutics
Good health and well-being
Openalex Percentile: Top 53%
Pharmacovigilance and Adverse Drug Reactions
DOISourceOpenAlex
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Antihypertensive drug-induced adverse events in patients aged 80 years and older: A retrospective analysis using the Japanese Adverse Drug Event Report Database — Riku Matsushima, Masayuki Hashiguchi, et al. · International Journal of Clinical Pharmacology and Therapeutics (2026) | TGRS Research Map | TGRS