Integration of quantitative MRI and liver function indices to predict early tumor response after stereotactic body radiotherapy for hepatocellular carcinoma: A prospective study

Early increases in ADC after SBRT of the liver were associated with tumor shrinkage and changes in PIVKA-II, supporting the use of quantitative MRI as an early response biomarker. Larger cohorts with longer follow-up periods are warranted.

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Publication Details

Journal
Clinical and Translational Radiation Oncology
Published
2026-02-22
DOI
https://doi.org/10.1016/j.ctro.2026.101137
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
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article

Integration of quantitative MRI and liver function indices to predict early tumor response after stereotactic body radiotherapy for hepatocellular carcinoma: A prospective study

M. Matsuo, Akihiro Ohbora, Shuto Nakaya, Kousei Adachi et al.
Clinical and Translational Radiation Oncology
Hepatocellular Carcinoma Treatment and Prognosis
article

Integration of quantitative MRI and liver function indices to predict early tumor response after stereotactic body radiotherapy for hepatocellular carcinoma: A prospective study

M. Matsuo, Akihiro Ohbora, Shuto Nakaya, Kousei Adachi, Osamu Tanaka, Takao Kojima, Takuya Taniguchi
article en

Abstract

Early increases in ADC after SBRT of the liver were associated with tumor shrinkage and changes in PIVKA-II, supporting the use of quantitative MRI as an early response biomarker. Larger cohorts with longer follow-up periods are warranted.

Clinical and Translational Radiation OncologyVol. 58
Asahi University (JP), Gifu University Hospital (JP)
Good health and well-being
Openalex Percentile: Top 48%
Hepatocellular Carcinoma Treatment and Prognosis
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