Point-of-Care EEG for Non-Convulsive Seizure and Status Epilepticus: Advances, Limitations, and Future Directions

Point-of-care electroencephalography (POC-EEG) has emerged as a practical tool for the rapid detection of non-convulsive seizures (NCS) and non-convulsive status epilepticus (NCSE) in acute neurological settings where access to conventional EEG is often delayed. This narrative review synthesizes current evidence on the clinical applications, tech-no-logical evolution, and limitations of POC-EEG systems across adult and pediatric populations. Available data suggest that POC-EEG is associated with earlier seizure identification, more timely antiseizure treatment decisions, and reduced dependence on inter-facility transfers in selected healthcare settings. Beyond seizure detection, POC-EEG has shown potential utility in the assessment of acute encephalopathy due to conditions such as stroke, traumatic brain injury, delirium, and post-cardiac arrest states. Recent advances in device portability and artificial intelligence-assisted interpretation have expanded accessibility, enabling use by non-specialist clinicians; however, reduced spatial resolution, artifact susceptibility, and variable performance in focal or low-burden epileptiform activity remain important limitations. Automated detection algorithms show high accuracy for sustained seizure burden but require cautious interpretation and further prospective validation. Ethical and health-system considerations, including equitable access, diagnostic stewardship, and data governance, are increasingly relevant as adoption grows. Overall, POC-EEG represents a promising adjunct to conventional EEG that may improve early diagnostic workflows in acute neurological care, while definitive impacts on long-term outcomes warrant further study.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-02-22
DOI
https://doi.org/10.3390/jcm15041643
Primary Topic
EEG and Brain-Computer Interfaces
Type
article
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article

Point-of-Care EEG for Non-Convulsive Seizure and Status Epilepticus: Advances, Limitations, and Future Directions

P U Shah, Zehra H. Jaffri, Jamir Pitton Rissardo, Manisha Koneru et al.
Journal of Clinical Medicine
EEG and Brain-Computer Interfaces
article

Point-of-Care EEG for Non-Convulsive Seizure and Status Epilepticus: Advances, Limitations, and Future Directions

P U Shah, Zehra H. Jaffri, Jamir Pitton Rissardo, Manisha Koneru, Evren Burakgazi-Dalkilic, Ruchika Moturi, K. Piotrowski, A. Gribachov, Anusha Keshireddy, Ana Leticia Fornari Caprara, April Pivonka, Hana Rababeh, Haashim Khurram, Matthew George Petruncio
article en

Abstract

Point-of-care electroencephalography (POC-EEG) has emerged as a practical tool for the rapid detection of non-convulsive seizures (NCS) and non-convulsive status epilepticus (NCSE) in acute neurological settings where access to conventional EEG is often delayed. This narrative review synthesizes current evidence on the clinical applications, tech-no-logical evolution, and limitations of POC-EEG systems across adult and pediatric populations. Available data suggest that POC-EEG is associated with earlier seizure identification, more timely antiseizure treatment decisions, and reduced dependence on inter-facility transfers in selected healthcare settings. Beyond seizure detection, POC-EEG has shown potential utility in the assessment of acute encephalopathy due to conditions such as stroke, traumatic brain injury, delirium, and post-cardiac arrest states. Recent advances in device portability and artificial intelligence-assisted interpretation have expanded accessibility, enabling use by non-specialist clinicians; however, reduced spatial resolution, artifact susceptibility, and variable performance in focal or low-burden epileptiform activity remain important limitations. Automated detection algorithms show high accuracy for sustained seizure burden but require cautious interpretation and further prospective validation. Ethical and health-system considerations, including equitable access, diagnostic stewardship, and data governance, are increasingly relevant as adoption grows. Overall, POC-EEG represents a promising adjunct to conventional EEG that may improve early diagnostic workflows in acute neurological care, while definitive impacts on long-term outcomes warrant further study.

Journal of Clinical MedicineVol. 15(4)
University of Michigan (US), Cooper University Hospital (US), Cooper Medical School of Rowan University (US), Rowan University (US)
Openalex Percentile: Top 49%
EEG and Brain-Computer Interfaces
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