Lactylation-related genes contribute to neurological injury and prognosis of acute ischemic stroke based on transcriptome and single-cell sequencing analysis

Our findings reveal significant correlations between LRGs in AIS patients and both neurological deficit severity and inflammatory status, highlighting LRGs as potential prognostic biomarkers for AIS.

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Publication Details

Journal
Cell & Bioscience
Published
2026-02-22
DOI
https://doi.org/10.1186/s13578-026-01546-7
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
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article

Lactylation-related genes contribute to neurological injury and prognosis of acute ischemic stroke based on transcriptome and single-cell sequencing analysis

Jialei Yang, Lian Gu, Yun Liang, Lulu Zhu et al.
Cell & Bioscience
Neuroinflammation and Neurodegeneration Mechanisms
article

Lactylation-related genes contribute to neurological injury and prognosis of acute ischemic stroke based on transcriptome and single-cell sequencing analysis

Jialei Yang, Lian Gu, Yun Liang, Lulu Zhu, Jing Zeng, Miaomiao Xu, Li Su, Zihan Song, Xiaolan Huang, Jie Li
article en

Abstract

Our findings reveal significant correlations between LRGs in AIS patients and both neurological deficit severity and inflammatory status, highlighting LRGs as potential prognostic biomarkers for AIS.

Cell & BioscienceVol. 16(1)
Guangxi University (CN), Guangxi Medical University (CN), Guangxi University of Chinese Medicine (CN), Ruikang Affiliated Hospital of Guangxi Medical University (CN)
Good health and well-being
Openalex Percentile: Top 57%
Neuroinflammation and Neurodegeneration Mechanisms
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