Triglyceride glucose index—a body shape index (TyG-ABSI) outperforms traditional obesity indices in predicting all-cause and cardiovascular mortality in metabolic-dysfunction associated steatotic liver disease: the mediating role of biological aging

TyG-ABSI serves as a robust, independent predictor of mortality in patients with MASLD, outperforming traditional TyG-related metrics. The association is significantly associated with the pathway of accelerated biological aging, highlighting the utility of TyG-ABSI for enhanced risk stratification in clinical practice.

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Publication Details

Journal
Cardiovascular Diabetology
Published
2026-02-22
DOI
https://doi.org/10.1186/s12933-026-03112-4
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Triglyceride glucose index—a body shape index (TyG-ABSI) outperforms traditional obesity indices in predicting all-cause and cardiovascular mortality in metabolic-dysfunction associated steatotic liver disease: the mediating role of biological aging

Yifei FENG, Xin Qiu, Wenli He, Bangde Xiang et al.
Cardiovascular Diabetology
Liver Disease Diagnosis and Treatment
article

Triglyceride glucose index—a body shape index (TyG-ABSI) outperforms traditional obesity indices in predicting all-cause and cardiovascular mortality in metabolic-dysfunction associated steatotic liver disease: the mediating role of biological aging

Yifei FENG, Xin Qiu, Wenli He, Bangde Xiang, Jiayuan Zhang, Peishu Li, Guodong Yang, Shuang Shen
article en

Abstract

TyG-ABSI serves as a robust, independent predictor of mortality in patients with MASLD, outperforming traditional TyG-related metrics. The association is significantly associated with the pathway of accelerated biological aging, highlighting the utility of TyG-ABSI for enhanced risk stratification in clinical practice.

Cardiovascular DiabetologyVol. 25(1)
Ministry of Education of the People's Republic of China (CN), Guangxi Medical University (CN), First Affiliated Hospital of GuangXi Medical University (CN), The Second Nanning People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 47%
Liver Disease Diagnosis and Treatment
DOIOpen Access PDFOpenAlex
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Triglyceride glucose index—a body shape index (TyG-ABSI) outperforms traditional obesity indices in predicting all-cause and cardiovascular mortality in metabolic-dysfunction associated steatotic liver disease: the mediating role of biological aging — Yifei FENG, Xin Qiu, et al. · Cardiovascular Diabetology (2026) | TGRS Research Map | TGRS