Promising survival prospects and immunotherapy potential in polymerase epsilon-mutated endometrial cancer: a comprehensive systematic review and meta-analysis unveiling future therapeutic opportunities
POLE mutations in endometrial cancer are associated with a favorable prognosis and show promising potential for immunotherapy. Molecular subtyping that incorporates POLE mutation status should be considered standard practice for risk stratification and treatment planning.
Authors
- Cut Adeya Adella (ORCID: https://orcid.org/0000-0002-6981-6441)
- Felix Khosasi (ORCID: https://orcid.org/0009-0006-8828-861X)
- Elbert Elbert
Institutions
- Gynecologic Oncology Group (US)
- Universitas Sumatera Utara (ID)
Publication Details
- Journal
- Obstetrics & Gynecology Science
- Published
- 2026-02-22
- DOI
- https://doi.org/10.5468/ogs.25179
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitas Sumatera Utara