Development and Internal Evaluation of an Interpretable AI-Based Composite Score for Psychosocial and Behavioral Screening in Dental Clinics Using a Mamdani Fuzzy Inference System

<i>Background and Objectives:</i> Psychosocial symptoms and oral behaviors can complicate routine dental care, yet available screeners yield multiple separate scores. Explainable artificial intelligence offers a pragmatic way to integrate such multidomain measures into a single, auditable output that can support screening-oriented stratification and standardized documentation (non-diagnostic). Therefore, we aimed to develop an interpretable, deterministic Mamdani fuzzy inference system (FIS) integrating GAD-7, PHQ-9, and OBC-21 into a 0-10 psychobehavioral composite score (PCS) to support screening-oriented stratification and standardized documentation (non-diagnostic). <i>Materials and Methods:</i> Cross-sectional multicenter study in 18 private dental clinics in Romania (October 2024-March 2025; n = 460). A rule-based Mamdani Type-1 FIS was specified a priori (48 rules; triangular membership functions; centroid defuzzification) without supervised training. Internal evaluation assessed coherence across severity strata, robustness to predefined input perturbations (±1 point; ±5%) and membership-function variation (±10%), and benchmarking against linear composites (Z-mean; PCA PC1). <i>Results:</i> Median PCS was 2.30 (IQR 2.03-3.56). PCS correlated with GAD-7 (Spearman ρ = 0.886), PHQ-9 (ρ = 0.792), and OBC-21 (ρ = 0.687) (all <i>p</i> < 0.001), increased monotonically across anxiety and depression severity strata, and was higher in high OBC-21 risk. Robustness was excellent under input perturbations (ICC(3,1) = 0.983 for ±1 point; 0.992 for ±5%) and high under ±10% membership-function variation (ICC(3,1) = 0.959). Concordance with linear baselines was high (Spearman ρ = 0.956 for Z-mean; 0.955 for PCA PC1), with a small systematic nonlinearity at higher scores. <i>Conclusions:</i> PCS provides a fully auditable, rule-based integration of three patient-reported measures with coherent internal behavior and robustness to plausible measurement noise and specification changes. This study reports internal evaluation of a deterministic, rule-based aggregation; external clinical validation against independent outcomes is required before any clinical utility claims.

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Journal
Medicina
Published
2026-02-21
DOI
https://doi.org/10.3390/medicina62020412
Primary Topic
Dental Anxiety and Anesthesia Techniques
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article
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article

Development and Internal Evaluation of an Interpretable AI-Based Composite Score for Psychosocial and Behavioral Screening in Dental Clinics Using a Mamdani Fuzzy Inference System

Gabriela Ciavoi, Alexandra Lavinia Vlad, Anca Maria Fratila, Ioana Scrobota et al.
Medicina
Dental Anxiety and Anesthesia Techniques
article

Development and Internal Evaluation of an Interpretable AI-Based Composite Score for Psychosocial and Behavioral Screening in Dental Clinics Using a Mamdani Fuzzy Inference System

Gabriela Ciavoi, Alexandra Lavinia Vlad, Anca Maria Fratila, Ioana Scrobota, Florin Sandu Blaga, Raluca Ortensia Cristina Iurcov, Ioan Andrei Țig
article en

Abstract

<i>Background and Objectives:</i> Psychosocial symptoms and oral behaviors can complicate routine dental care, yet available screeners yield multiple separate scores. Explainable artificial intelligence offers a pragmatic way to integrate such multidomain measures into a single, auditable output that can support screening-oriented stratification and standardized documentation (non-diagnostic). Therefore, we aimed to develop an interpretable, deterministic Mamdani fuzzy inference system (FIS) integrating GAD-7, PHQ-9, and OBC-21 into a 0-10 psychobehavioral composite score (PCS) to support screening-oriented stratification and standardized documentation (non-diagnostic). <i>Materials and Methods:</i> Cross-sectional multicenter study in 18 private dental clinics in Romania (October 2024-March 2025; n = 460). A rule-based Mamdani Type-1 FIS was specified a priori (48 rules; triangular membership functions; centroid defuzzification) without supervised training. Internal evaluation assessed coherence across severity strata, robustness to predefined input perturbations (±1 point; ±5%) and membership-function variation (±10%), and benchmarking against linear composites (Z-mean; PCA PC1). <i>Results:</i> Median PCS was 2.30 (IQR 2.03-3.56). PCS correlated with GAD-7 (Spearman ρ = 0.886), PHQ-9 (ρ = 0.792), and OBC-21 (ρ = 0.687) (all <i>p</i> < 0.001), increased monotonically across anxiety and depression severity strata, and was higher in high OBC-21 risk. Robustness was excellent under input perturbations (ICC(3,1) = 0.983 for ±1 point; 0.992 for ±5%) and high under ±10% membership-function variation (ICC(3,1) = 0.959). Concordance with linear baselines was high (Spearman ρ = 0.956 for Z-mean; 0.955 for PCA PC1), with a small systematic nonlinearity at higher scores. <i>Conclusions:</i> PCS provides a fully auditable, rule-based integration of three patient-reported measures with coherent internal behavior and robustness to plausible measurement noise and specification changes. This study reports internal evaluation of a deterministic, rule-based aggregation; external clinical validation against independent outcomes is required before any clinical utility claims.

MedicinaVol. 62(2)
Lucian Blaga University of Sibiu (RO), University of Oradea (RO), Clinical Emergency Hospital Bucharest (RO)
Openalex Percentile: Top 48%
Dental Anxiety and Anesthesia Techniques
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