Annexin A1 exacerbates islet stellate cell activation by regulating triglyceride catabolism via the PPARα/ACOX1/CYP4a pathway
ANXA1 promotes ISCs activation by enhancing triglyceride catabolism through the PPARα signaling pathway, suggesting a novel therapeutic target for islet fibrosis.
Authors
- Peter J.H. Jones (ORCID: https://orcid.org/0000-0001-5887-2846)
- Xia Liu (ORCID: https://orcid.org/0000-0002-9209-0562)
- Rui Li (ORCID: https://orcid.org/0000-0001-5953-2341)
- Tianpei Yu
- Qian Lv
- Yi-Xiang Wang (ORCID: https://orcid.org/0000-0002-4021-4228)
- HouFa Geng
- Qinqin Qiu
- Yiquan Sang
- Li Shi
- Wei Xu
- Ben Wang
- Jun Liang
- Qing Li
- Yan Zhang
Institutions
- Xuzhou Medical College (CN)
- King's College London (GB)
- King's College School (GB)
- Xuzhou Central Hospital (CN)
- Lux Research (United States) (US)
- Cixian People's Hospital (CN)
Publication Details
- Journal
- Islets
- Published
- 2026-02-22
- DOI
- https://doi.org/10.1080/19382014.2026.2633793
- Primary Topic
- S100 Proteins and Annexins
- Type
- article
- Field-Weighted Citation Impact
- 0.00