Low-dose lamotrigine co-administration decreases quetiapine plasma concentrations: Effect of UGT2B7-161C>T polymorphism in Japanese patients with depression
The present study provides evidence that low-dose lamotrigine co-administration decreases plasma quetiapine concentrations in Japanese patients with depression and that the magnitude of this effect differs between genotypes of the <i>UGT2B7</i> -161C>T polymorphism.
Authors
- Yoko Tomori (ORCID: https://orcid.org/0000-0002-6280-0754)
- Kenji Nemoto (ORCID: https://orcid.org/0000-0002-1210-5833)
- A. Nakamura (ORCID: https://orcid.org/0000-0003-3629-9537)
- Shoko Kagawa (ORCID: https://orcid.org/0000-0001-6994-6687)
- Kazuo Mihara
- Tsuyoshi Kondo
- Goyo Nagai
- Takeshi Suzuki
Publication Details
- Journal
- International Journal of Clinical Pharmacology and Therapeutics
- Published
- 2026-02-22
- DOI
- https://doi.org/10.5414/cp204879
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00