Susceptibility of <i>Phthorimaea absoluta</i> ( <scp>Meyrick</scp> ) ( <scp>Lepidoptera: Gelechiidae</scp> ) to novel and established insecticides in <scp>Brazil</scp> : resistance survey, baseline, and implications for management

P. absoluta populations are susceptible to isocycloseram and tolfenpyrad, but early tolerance shifts signal emerging adaptive responses that merit close monitoring. The enzymatic associations observed highlight the central role of metabolic detoxification in shaping susceptibility and potential cross-resistance. Overall, the new chemistries remain useful options for P. absoluta control, but their long-term effectiveness depends on early identification of susceptibility shifts and incorporating metabolic insights into resistance management strategies. © 2026 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.